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Royal Mail's sister business GLS to buy 20% stake in Greece's ACS for $80 million

  • Parcel services firm GLS, the international sister business to the UK's Royal Mail, has agreed to buy a 20% stake in Greece's ACS for 74 million euros ($80.06 million), their parent International Distribution Services said on Monday.
    10/21/2024

Royal Mail, GLS need sizable investments soon, billionaire suitor Kretinsky says

  • Royal Mail and its international parcels network GLS need sizable, almost immediate investments to defend market share and face shifting market trends, Czech billionaire Daniel Kretinsky told Reuters on Wednesday after the group's owner agreed to a 3.57 billion pound ($4.55 billion) takeover.
    05/29/2024
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Cell Reports Medicine Publication Demonstrates How Gelesis' Oral Therapeutic Hydrogel Promotes Weight Loss and Metabolic Health by Targeting the Gut-Liver Axis in Pre-Clinical Studies

  • BOSTON--(BUSINESS WIRE)---- $GLS #earnings--A new paper published today in Cell Reports Medicine suggests that weight loss resulting from Gelesis' superabsorbent hydrogel treatment is not only a result of its space-occupying properties; the mechanical composition and structure of the material may have notable benefits for gut and metabolic health. The continued rise in obesity and type 2 diabetes has led to the increasing prevalence of fatty liver disease worldwide and highlights the urgent need for therapies tha.
    Tue, Oct. 17, 2023

Gelesis Holdings, Inc. (GLS) Q3 2022 Earnings Call Transcript

  • Gelesis Holdings, Inc. (NYSE:GLS ) Q3 2022 Earnings Conference Call November 14, 2022 8:30 AM ET Company Participants Anna Kate Heller - IR Yishai Zohar - Founder and CEO Elliot Maltz – CFO Conference Call Participants Daniel Grosslight - Citi Operator Hello, and welcome to the Gelesis Third Quarter 2022 Earnings Conference Call. My name is Elliot, and I'll be coordinating your call today.
    Mon, Nov. 14, 2022

Gelesis Reports Third Quarter 2022 Results

  • BOSTON--(BUSINESS WIRE)--Gelesis Holdings, Inc. (NYSE: GLS) (“Gelesis” or the “Company”), the maker of Plenity for weight management, today reported financial results for the third quarter of 2022. Plenity is a novel orally administered, FDA-cleared weight management therapy that helps people feel satisfied with smaller portions, so they can eat less and lose weight, while still enjoying the foods they love. Plenity is the only FDA-cleared aid for weight management for people with a BMI as low as 25, up to a BMI of 40, with the largest addressable market of any prescription weight management approach on the market today. “We continued to see strong uptake of Plenity among consumers and physicians in the third quarter with 114% topline growth this quarter compared to the prior year period as well as 36% of additional gross margin. Despite a significant reduction in marketing spend compared to the first two quarters this year, we acquired over 23,500 new members and sold over 92,000 units during the third quarter of 2022, more than twice as many units as we sold in the prior year quarter. As expected, the reduced level of marketing investment had an impact on revenues this quarter, in line with our current guidance,” said Yishai Zohar, Founder and CEO of Gelesis. “We believe that to take advantage of Plenity’s differentiated profile, affordability, and broad label, Plenity should be widely available and easily accessible, and I am excited to announce that we are pursuing an application with the FDA to change the classification of Plenity to over-the-counter, which would make it available without the need for a prescription. If approved, Plenity would become only one of two FDA-regulated oral treatments for weight management available without a prescription. Importantly for Gelesis, the change to OTC should improve our cost of acquiring new members and allow other cost reductions associated with the prescription granting process, thereby reducing our reliance on capital markets to reach profitability. We believe we will be able to grow sales more efficiently as we potentially open up new sales channels and build towards the long-term potential of Plenity. “Now is the right time to pursue an OTC pathway based on Plenity’s best in class safety data, as demonstrated in over 185,000 patients. An effective, affordable, and trusted personal weight management product like Plenity available over the counter will be a game changer for individuals struggling with excess weight. We intend to submit our application to the FDA in the coming months and could potentially receive market clearance by the middle of next year. We are confident that an OTC classification, if approved, will enhance our ability to acquire new members and allow other cost reductions associated with the prescription granting process while sustaining revenue growth in a capital efficient way, thus reducing our reliance on the capital markets to reach profitability.” Key Business Metrics For the Three Months Ended September 30, For the Nine Months Ended September 30, 2022 2021 2022 2021 In thousands (Unaudited) (Unaudited) (Unaudited) (Unaudited) New members acquired 23,500 15,700 107,700 44,000 Units sold 92,070 45,825 336,530 132,602 Product revenue, net $ 6,443 $ 3,014 $ 22,930 $ 8,293 Average selling price per unit, net $ 69.98 $ 65.77 $ 68.14 $ 62.54 Gross profit $ 2,827 $ 251 $ 9,615 $ 709 Gross margin 44% 8% 42% 9% Third Quarter 2022 Results Product revenue, net, was $6.4 million for the third quarter 2022 compared to $3.0 million for the third quarter 2021, a 114% increase year-over-year. A total of 23,500 members joined during third quarter 2022 compared to 15,700 members joined during the third quarter 2021, a 50% increase year-over-year, while 92,070 units were sold during the third quarter 2022 compared to 45,825 during the third quarter 2021, a 101% increase year-over-year. Gross profit was $2.8 million for the third quarter 2022 compared to $0.2 million for the third quarter 2021, with gross margin for the third quarter 2022 increasing to 44% from 8% in the third quarter 2021, attributable to increased sales volume and lower costs of goods sold per unit. Net loss was $(14.1) million and Adjusted EBITDA was $(12.3) million for the third quarter 2022, compared to net loss of $(30.7) million and Adjusted EBITDA of $(26.2) million for the third quarter 2021. A reconciliation of Adjusted EBITDA, a non-GAAP financial measure, to net loss, its most comparable financial measure under generally accepted accounting principles in the United States (“U.S. GAAP”), is included in the tables accompanying this press release. See “Non-GAAP Financial Measures” for additional important information regarding Adjusted EBITDA. Recent Business Highlights Gelesis is preparing an application to the FDA to change the classification of Plenity from prescription-only to be available over the counter (“OTC”). An OTC classification would make Plenity widely available and easily accessible, empowering individuals struggling with excess weight with an easier path to an effective, affordable, and trusted weight management product. With Plenity’s unprecedented safety and efficacy profiles, demonstrated in over 185,000 patients, the Company believes this is the optimal time to pursue an OTC pathway with the FDA. Based on Gelesis’ timelines, Plenity could receive clearance from the FDA to market as an OTC product by the middle of 2023. Earlier this month, Dr. Frank Greenway, principal investigator, presented data from Gelesis’ LIGHT-UP Study at Obesity Week. Waist to Height Ratio, known to be correlated with insulin resistance and metabolic syndrome, was a predictor of weight loss response in the study based on a post-hoc analysis. Gelesis presented additional data at Obesity Week demonstrating that its investigational clinical-stage hydrogel, Gel-B, preferentially enhances the growth of Akkermansia muciniphilia in preclinical models compared to prebiotics. Akkermansia muciniphilia is a bacteria associated with thickened mucosal lining of the gut, that encourages improved gut barrier function, and lean body mass. In August, Gelesis presented its LIGHT-UP study at the International Congress of Endocrinology in Singapore. Clinical data from the study suggests that Gelesis’ new oral hydrogel, GS200, may improve insulin sensitivity and favorably impact metabolic syndrome. The 25-week study also examined the effects of GS200 on insulin resistance, indicating it is helpful in improving weight loss among those with prediabetes and type-2 diabetes. In July and August, Gelesis completed a private placement of $25.0 million in promissory notes with existing top tier shareholders. Financial Outlook for Fiscal Year 2022 The Company is reiterating its guidance for the full year fiscal year 2022: Product revenue, net, to be in the range of $27.0 million to $30.0 million. Gross profit to be in the range of $11.0 million to $13.0 million. Adjusted EBITDA to be in the range of $(75.0) million to $(80.0) million. The guidance provided above constitutes forward-looking statements which are subject to uncertainty. Actual results may differ materially. Refer to the “Forward-Looking Statements” safe harbor section below for information on the factors that could cause our actual results to differ materially from these forward-looking statements. Conference Call and Webcast Information Gelesis management will host a conference call today at 8:30 am ET to discuss the third quarter 2022 results, followed by a question-and-answer period. The live call can be accessed via webcast on the “Events & Presentations” section of the Gelesis Investor Relations website at https://ir.gelesis.com/. The webcast will also be archived and available for replay shortly after the call has concluded. Those who are interested in participating in the live call can dial 844-200-6205 from the U.S. and 929-526-1599 internationally and enter the access code 849038. About Gelesis Gelesis Holdings Inc. (NYSE: GLS) (“Gelesis”) is a consumer-centered biotherapeutics company and the maker of Plenity®, which is inspired by nature and FDA cleared to aid in weight management. Our first-of-their-kind non-systemic superabsorbent hydrogels are made entirely from naturally derived building blocks. They are inspired by the composition and mechanical properties of raw vegetables, taken by capsule, and act locally in the digestive system, so people feel satisfied with smaller portions. Our portfolio includes Plenity® and potential therapies in development for patients with Type 2 Diabetes, Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH), and Functional Constipation. For more information, visit gelesis.com, or connect with us on Twitter @GelesisInc. Plenity® is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 25–40 kg/m², when used in conjunction with diet and exercise. Important Safety Information about Plenity Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. For all medications that should be taken without food (on an empty stomach), continue taking on an empty stomach or as recommended by your physician. For all medications that should be taken with food, take them after starting a meal. For all medications that should be taken without food (on an empty stomach), continue taking on an empty stomach or as recommended by your physician. The overall incidence of side effects with Plenity was no different than placebo. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Contact a doctor right away if problems occur. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. Rx Only. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY. Forward-Looking Statements Certain statements, estimates, targets and projections in this press release may constitute “forward-looking statements” within the meaning of the federal securities laws. The words “anticipate,” “believe,” continue,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “strive,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that statement is not forward looking. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Forward-looking statements include, but are not limited to, statements regarding Gelesis’ or its management team’s expectations, hopes, beliefs, intentions or strategies regarding the future, including those relating to Gelesis’ expected operating and financial performance and market opportunities. In addition, any statements that refer to guidance, projections, forecasts, or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and Gelesis assumes no obligation and does not intend to update or revise these forward-looking statements, whether as a result of new information, future events, or otherwise. Gelesis gives no assurance that any expectations set forth in this press release will be achieved. Various risks and uncertainties (some of which are beyond Gelesis’ control) or other factors could cause actual future results, performance or events to differ materially from those described herein. Some of the factors that may impact future results and performance may include, without limitation: (i) the ability of Gelesis to raise financing, if and when needed and/or to issue or sell common stock pursuant to our committed equity financing agreement; (ii) the ability of Gelesis to continue as a going concern; (iii) Gelesis’ ability to achieve and maintain widespread market acceptance of Plenity; (iv) the impact of current and future applicable laws and regulations and Gelesis’ ability to comply with such laws and regulations; (v) Gelesis’ ability to produce adequate supply of Plenity, including Gelesis’ ability to continue to invest in manufacturing capacity and to build additional manufacturing sites; (vi) the development of the telehealth market and regulations related to remote healthcare; (vii) global economic, political and social conditions and uncertainties in the markets that Gelesis serves, including risks and uncertainties caused by the COVID-19 pandemic or other natural or man-made disasters; (viii) Gelesis’ ability to enter into strategic collaborations, to acquire businesses or products or form strategic alliances and to realize the benefits of such collaborations, acquisitions and alliances; (ix) the level of demand, and willingness of potential members to pay out-of-pocket for, Plenity; (x) the ability of Gelesis to enforce its intellectual property rights and proprietary technology ; (xi) the risk that a third-party’s activities, including with respect to third parties that Gelesis has granted out licenses to or granted limited exclusive or non-exclusive commercial rights, may overlap or interfere with the commercialization of Plenity; (xii) Gelesis’ ability to successfully develop and expand its operations and manufacturing and to effectively manage such growth; (xiii) Gelesis’ business partners’ ability to successfully launch and commercialize Plenity in certain key markets; (xiv) risk relating to the loss of Gelesis’ suppliers or distributors, or their inability to provide adequate supply of materials or distribution; (xv) the risk that Gelesis’ business partners may experience significant disruptions in their operations; (xvi) Gelesis’ ability to retain its senior executive officers and to attract and keep senior management and key scientific and commercial personnel; (xvii) Gelesis’ ability to identify and discover additional product candidates and to obtain and maintain regulatory approval for such candidates, including GS200; (xviii) risks related to potential product liability exposure for Plenity, GS200, or other future product candidates; (xix) risks related to adverse publicity in the weight management industry, changes in the perception of Gelesis’ brands, and the impact of negative information or inaccurate information about Gelesis on social media; (xx) Gelesis’ ability to enhance its brand recognition, increase distribution of Plenity and generate product sales and reduce operating losses going forward; (xxi) the impact of risks associated with economic, financial, political, environmental and social matters and conditions on Gelesis’ supply chain, its manufacturing operations and other aspects of its business; (xxii) Gelesis’ ability to accurately forecast revenue and appropriately monitor its associated expenses in the future; (xxiii) Gelesis’ ability to compete against other weight management and wellness industry participants or other more effective or more favorably perceived weight management methods, including pharmaceuticals, devices and surgical procedures; (xxiv) foreign currency fluctuations and inflation; (xxv) the risk that Gelesis fails to maintain adequate operational and financial resources or to raise additional capital or generate sufficient cash flows; (xxvi) Gelesis’ ability to successfully protect against security breaches and other disruptions to its information technology structure; (xxvii) the ability of Gelesis to maintain its listing on the New York Stock Exchange; (xxviii) failure to realize the anticipated benefits of the business combination; (xxix) our ability to successfully pursue OTC classification for Plenity and the timing for market clearance of such classification; and (xxx) other important factors discussed in the “Risk Factors” section of Gelesis’ most recent Annual Report on Form 10-K and in other filings that Gelesis makes with the Securities and Exchange Commission. These filings address other important risks and uncertainties that could cause actual results and events to differ materially from those contained in the forward-looking statements. Disclaimer Gelesis assumes no obligation and does not intend to update or revise the results provided in this press release. The results provided in this press release represent past performance and are not necessarily predictive of future results. Plans to Make Plenity Available Without a Prescription We believe Plenity’s advantages are its differentiated safety-to-efficacy profile, broad approved labeling, and affordability to the consumer. Accordingly, we believe it is important that Plenity be widely available and easily accessible to consumers. We plan to pursue an application with the FDA to change Plenity's classification in the United States from prescription-only to over-the-counter. In addition to making Plenity more accessible to people struggling with excess weight, we believe making Plenity available over-the-counter could reduce costs associated with acquiring new members and allow us to reduce costs associated with the prescription granting process, while also enabling new sales channels for the Company. We plan to submit our application to the FDA during the first quarter of 2023 and could receive market clearance by the third quarter of 2023. Key Business Metrics We monitor the following key metrics to help us evaluate our business, identify trends affecting our business, formulate business plans and make strategic decisions. We believe the following metrics are useful in evaluating our business: New members acquired We define new members acquired as the number of consumers in the United States who have begun their weight loss journey with Plenity during the financial period presented. This is the total number of recurring and non-recurring consumers who have begun their weight loss journey during the financial period presented. We do not differentiate from recurring and non-recurring consumers as of this date as (i) we strongly believe every member’s weight-loss journey is chronic and long-term in nature, and (ii) we have not initiated our long-term strategy and mechanisms to retain and/or win-back members. We will continue to evaluate the utility of this business metric in future periods. Units sold Units sold is defined as the number of 28-day supply units of Plenity sold through strategic partnerships with online pharmacies and telehealth providers as well as the units sold to our strategic partners outside the United States. Note that the terms “units” and “monthly kits”, as mentioned in Gelesis’ various public disclosures and filings, are synonymous when used to describe the sales volume of Plenity. Product revenue, net We recognize product revenue in accordance with Accounting Standards Codification Topic 606, Revenue from Contracts with Customers, when we transfer promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. Our product revenue is derived from product sales of Plenity, net of estimates of variable consideration for which reserves are established for expected product returns, shipping charges to end-users, pharmacy dispensing and platform fees, merchant and processing fees, and promotional discounts offered to end-users. Average selling price per unit, net Average selling price per unit, net is the gross price per unit sold during the period net of estimates of per unit variable consideration for which reserves are established for expected product returns, shipping charges to end-users, pharmacy dispensing and platform fees, merchant and processing fees, and promotional discounts offered to end-users. Gross profit and gross margin Our gross profit represents product revenue, net, less our total cost of goods sold, and our gross margin is our gross profit expressed as a percentage of our product revenue, net. Our gross profit and gross margin have been and will continue to be affected by a number of factors, including the prices we charge for our product, the costs we incur from our vendors for certain components of our cost of goods sold, the mix of channel sales in a period, and our ability to sell our inventory. Non-GAAP Financial Measures In addition to our financial results determined in accordance with GAAP, we believe that Adjusted EBITDA, a non-GAAP measure, is useful in evaluating our operating performance. We define “Adjusted EBITDA” as net (loss) income before depreciation and amortization expenses, provision for (benefit from) income taxes, interest expense, net, stock-based compensation and (gains) and losses related to changes in fair value of our warrant liability, our convertible promissory note liability, our tranche rights liability, our earnout liability and the One S.r.l. call option. We use Adjusted EBITDA to evaluate our ongoing operations and for internal planning and forecasting purposes because it facilitates internal comparisons of our historical operating performance. We believe that this non-GAAP financial measure, when taken together with the corresponding GAAP financial measure, net loss, provides meaningful supplemental information regarding our performance by excluding certain items that may not be indicative of our business, results of operations, or outlook. We consider Adjusted EBITDA to be an important measure because it helps illustrate underlying trends in our business and our historical operating performance on a more consistent basis. We believe that Adjusted EBITDA is helpful to our investors as it is a metric used by management in assessing the health of our business and our operating performance. However, non-GAAP financial information is presented for supplemental informational purposes only, has limitations as an analytical tool and should not be considered in isolation or as a substitute for financial information presented in accordance with GAAP. In addition, other companies, including companies in our industry, may calculate similarly titled non-GAAP financial measures differently or may use other measures to evaluate their performance, all of which could reduce the usefulness of Adjusted EBITDA as a tool for comparison. A reconciliation is provided below for Adjusted EBITDA to the most directly comparable financial measure stated in accordance with GAAP. Investors are encouraged to review the related GAAP financial measure and the reconciliation of this non-GAAP financial measure to its most directly comparable GAAP financial measure, and not to rely on any single financial measure to evaluate our business. SELECTED UNAUDITED CONDENSED CONSOLIDATED BALANCE SHEETS (In thousands) September 30, December 31, 2022 2021 ASSETS Cash and cash equivalents $ 24,847 $ 28,397 Accounts receivable and grants receivable 5,564 9,903 Inventories 18,411 13,503 Property and equipment, net 55,152 58,515 All other current and non-current assets 26,543 35,983 Total assets $ 130,517 $ 146,301 LIABILITIES, REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ DEFICIT Accounts payable $ 7,969 $ 10,066 Accrued expenses and other current liabilities 12,256 13,660 Deferred income, current portion 28,895 32,370 Notes and convertible notes payable, current portion 30,101 29,078 Warrant liabilities 590 15,821 Earnout liability 3,376 — Deferred income, non-current portion 8,150 8,914 Notes payable, non-current portion 26,716 35,131 All other current and non-current liabilities 5,585 7,648 Total liabilities 123,638 152,688 Noncontrolling interest 10,474 11,855 Redeemable convertible preferred stock — 311,594 Total stockholders’ deficit (3,595) (329,836) Total liabilities, noncontrolling interest, redeemable convertible preferred stock and stockholders’ deficit $ 130,517 $ 146,301 UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (In thousands) For the Three Months Ended September 30, For the Nine Months Ended September 30, 2022 2021 2022 2021 Revenue: Product revenue, net $ 6,443 $ 3,014 $ 22,930 $ 8,293 Licensing revenue 209 — 209 — Total revenue, net 6,652 3,014 23,139 8,293 Operating expenses: Costs of goods sold 3,616 2,763 13,315 7,584 Selling, general and administrative 17,032 24,725 87,188 50,642 Research and development 3,365 3,238 16,298 13,206 Amortization of intangible assets 567 567 1,700 1,700 Total operating expenses 24,580 31,293 118,501 73,132 Loss from operations (17,928 ) (28,279 ) (95,362 ) (64,839 ) Change in the fair value of earnout liability 2,814 — 55,495 — Change in the fair value of convertible promissory notes (852 ) — (1,008 ) — Change in the fair value of warrants 540 (2,231 ) 6,624 (9,282 ) Interest expense, net (164 ) (361 ) (485 ) (949 ) Other income, net 1,441 141 2,371 1,032 Loss before income taxes (14,149 ) (30,730 ) (32,365 ) (74,038 ) Provision for income taxes — — — 17 Net loss (14,149 ) (30,730 ) (32,365 ) (74,055 ) Accretion of Legacy Gelesis senior preferred stock to redemption value — (23,111 ) (37,934 ) (139,237 ) Accretion of noncontrolling interest put option to redemption value (80 ) (95 ) (253 ) (285 ) Net loss attributable to common stockholders $ (14,229 ) $ (53,936 ) $ (70,552 ) $ (213,577 ) Net loss per share attributable to common stockholders—basic and diluted $ (0.20 ) $ (9.61 ) $ (1.02 ) $ (38.19 ) Weighted average common shares outstanding—basic and diluted 72,772,627 5,615,192 69,349,679 5,592,931 UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (In thousands) For the Nine Months Ended September 30, 2022 2021 Cash flows from operating activities: Net loss $ (32,365 ) $ (74,055 ) Adjustments to reconcile net loss to net cash used in operating activities: . Amortization of intangible assets 1,700 1,700 Reduction in carrying amount of right-of-use assets 343 133 Depreciation 2,133 591 Stock-based compensation 26,539 4,180 Issuance of common stock commitment shares 500 — Gain on sales of common stock (1 ) — Unrealized loss on foreign currency transactions 1,305 132 Non-cash interest (income) expense (29 ) 65 Gain on CMS amendment (209 ) — Loss on One S.r.l. amendment 278 — Accretion on marketable securities — (1 ) Change in the fair value of earnout liability (55,495 ) — Change in the fair value of warrants (6,624 ) 9,282 Change in the fair value of convertible promissory notes 1,008 — Change in fair value of One S.r.l. call option (808 ) 601 Change in fair value of interest rate swap contract (758 ) 95 Changes in operating assets and liabilities: Account receivables (745 ) 618 Grants receivable 3,407 (1,145 ) Prepaid expenses and other current assets 5,246 (5,981 ) Inventories (4,928 ) (4,470 ) Other assets 229 (5,137 ) Accounts payable (1,758 ) 3,278 Accrued expenses and other current liabilities 2,742 16,161 Operating lease liabilities (341 ) (123 ) Deferred income (2,799 ) 34,542 Other long-term liabilities (23 ) (6,861 ) Net cash used in operating activities (61,453 ) (26,395 ) Cash flows from investing activities: Purchases of property and equipment (8,473 ) (18,383 ) Maturities of marketable securities — 24,000 Net cash (used in) provided by investing activities (8,473 ) 5,617 Cash flows from financing activities: Proceeds from Business Combination, net of transaction costs 70,479 Principal repayment of notes payable (1,342 ) (226 ) Repayment of convertible promissory notes, held at fair value (27,284 ) — Proceeds from convertible promissory notes, held at fair value 25,000 — Proceeds from issuance of promissory notes — 5,679 Proceeds from exercise of warrants 4 10 Proceeds from exercise of share-based awards 110 9 Proceeds from sales of common stock, net of issuance costs 39 — Net cash provided by financing activities 67,006 5,472 Effect of exchange rates on cash (630 ) (816 ) Net decrease in cash (3,550 ) (16,122 ) Cash and cash equivalents at beginning of year 28,397 48,144 Cash and cash equivalents at end of period $ 24,847 $ 32,022 Noncash investing and financing activities: Purchases of property and equipment included in accounts payable and accrued expense $ 958 $ 2,086 Deferred financing costs included in accounts payable and accrued expense $ — $ 564 Recognition of earnout liability $ 58,871 $ — Recognition of private placement warrant liability $ 8,140 $ — Acquisitions of right-of-use assets under operating leases $ 101 $ 190 Supplemental cash flow information: Interest paid on notes payable $ 233 $ 199 NET LOSS TO ADJUSTED EBITDA RECONCILIATION (In thousands, Unaudited) For the Three Months Ended September 30, For the Nine Months Ended September 30, 2022 2021 2022 2021 In thousands (Unaudited) (Unaudited) (Unaudited) (Unaudited) Adjusted EBITDA Net loss $ (14,149 ) $ (30,730 ) $ (32,365 ) $ (74,055 ) Provision for income taxes — — — 17 Depreciation and amortization 1,260 800 3,833 2,291 Stock based compensation expense 4,574 1,086 26,539 4,180 Change in fair value of earnout liability (2,814 ) — (55,495 ) — Change in fair value of warrants (540 ) 2,231 (6,624 ) 9,282 Change in fair value of convertible promissory notes 852 — 1,008 — Change in fair value of One S.r.l. call option (1,673 ) 47 (808 ) 601 Interest expense, net 164 361 485 949 Adjusted EBITDA $ (12,326 ) $ (26,205 ) $ (63,427 ) $ (56,735 )
    Mon, Nov. 14, 2022

Dr. Frank Greenway to Present Data from the LIGHT-UP Study with Gelesis' Oral Hydrogel Treatment GS200 at Obesity Week

  • BOSTON--(BUSINESS WIRE)--Gelesis Holdings Inc. (NYSE: GLS) (“Gelesis” or the “Company”) the maker of Plenity for weight management, today announced Dr. Frank Greenway will give an oral presentation at Obesity Week in San Diego, on Wednesday, November 2 at 4:00pm PDT.
    Tue, Nov. 01, 2022

Genesis League Sports to Airdrop Governance Tokens to Splinterlands Token Stakers

  • Media, Pennsylvania, Oct. 26, 2022 (GLOBE NEWSWIRE) — On October 25th at 14:00 UTC, Genesis League Sports (GLS) began its year-long airdrop of its $GLX tokens to current Splinterlands $SPS stakers. The parent company, Splinterlands, named from its popular fantasy-based strategy card game built on the blockchain, has had a loyal and enthusiastic user base… The post Genesis League Sports to Airdrop Governance Tokens to Splinterlands Token Stakers appeared first on DKODING...
    Wed, Oct. 26, 2022
SEC Filings
SEC Filings

Gelesis Holdings, Inc. (GLS) - 4

  • SEC Filings
  • 09/21/2023

Gelesis Holdings, Inc. (GLS) - 4

  • SEC Filings
  • 06/14/2023

Gelesis Holdings, Inc. (GLS) - 4

  • SEC Filings
  • 05/31/2023

Gelesis Holdings, Inc. (GLS) - 4

  • SEC Filings
  • 05/03/2023

Gelesis Holdings, Inc. (GLS) - 25-NSE

  • SEC Filings
  • 04/26/2023

Gelesis Holdings, Inc. (GLS) - EFFECT

  • SEC Filings
  • 03/31/2023

Gelesis Holdings, Inc. (GLS) - EFFECT

  • SEC Filings
  • 03/31/2023

Gelesis Holdings, Inc. (GLS) - POS AM

  • SEC Filings
  • 03/28/2023

Gelesis Holdings, Inc. (GLS) - 424B3

  • SEC Filings
  • 03/03/2023

Gelesis Holdings, Inc. (GLS) - 424B3

  • SEC Filings
  • 03/02/2023

Gelesis Holdings, Inc. (GLS) - 25-NSE

  • SEC Filings
  • 01/20/2023

Gelesis Holdings, Inc. (GLS) - SC 13D

  • SEC Filings
  • 12/30/2022

Gelesis Holdings, Inc. (GLS) - 4

  • SEC Filings
  • 11/22/2022

Gelesis Holdings, Inc. (GLS) - 424B3

  • SEC Filings
  • 11/16/2022

Gelesis Holdings, Inc. (GLS) - 424B3

  • SEC Filings
  • 10/03/2022

Gelesis Holdings, Inc. (GLS) - 424B3

  • SEC Filings
  • 09/16/2022

Gelesis Holdings, Inc. (GLS) - EFFECT

  • SEC Filings
  • 09/07/2022

Gelesis Holdings, Inc. (GLS) - EFFECT

  • SEC Filings
  • 09/07/2022

Gelesis Holdings, Inc. (GLS) - 424B3

  • SEC Filings
  • 09/06/2022

Gelesis Holdings, Inc. (GLS) - UPLOAD

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  • 08/25/2022

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Clinical Data from the LIGHT-UP Study Presented at the International Congress of Endocrinology Suggests New Gelesis Oral Hydrogel May Improve Insulin Sensitivity and Favorably Impact Metabolic Syndrome

  • BOSTON–(BUSINESS WIRE)–Gelesis Holdings Inc. (NYSE: GLS) (“Gelesis” or the “Company”) the maker of Plenity for weight management, today released a poster presentation at the International Congress of Endocrinology in Singapore. The LIGHT-UP study evaluated the safety and efficacy of GS200, an investigational oral hydrogel, which was designed to emulate the properties of ingested raw vegetables, […]...
  • 08/26/2022

Gelesis Holdings, Inc. (GLS) CEO Yishai Zohar on Q2 2022 Results - Earnings Call Transcript

  • Gelesis Holdings, Inc. (NYSE:GLS ) Q2 2022 Earnings Conference Call August 15, 2022 8:30 AM ET Company Participants Anna Heller - IR Yishai Zohar - Founder & CEO Elliot Maltz - CFO David Pass - COO & CCO Conference Call Participants Operator Hello, everyone. And welcome to the Gelesis' Second Quarter 2022 Earnings Conference Call.
  • 08/15/2022

Gelesis Reports Second Quarter 2022 Results

  • BOSTON--(BUSINESS WIRE)--Gelesis (NYSE: GLS), the maker of Plenity for weight management, today reported financial results for the second quarter of 2022. “We are seeing both consumers and clinicians embracing Plenity, with continued growth in both of our distribution channels. We are excited by the fact that consumers are ordering quarterly kits at the start of their treatment journey as well as by our refill rates,” said Yishai Zohar, Founder and CEO of Gelesis. “There has been incredible momentum in obesity care and finally, patients have multiple effective approaches to managing their weight based upon their BMI, insurance coverage, and their personal needs. Plenity offers a unique solution: orally administered capsules for those individuals with overweight and obesity across a wide BMI spectrum, including those that are looking to lose 15-30 pounds. Plenity is further differentiated by its strong safety profile – enabling people to lose weight while enjoying the foods they love – at an affordable price, making our business well positioned in this rising tide of obesity care.” “We’re encouraged by the continued growth in Plenity sales and improving profit margin, while our marketing efforts are getting more efficient by the day in generating awareness among consumers,” Gelesis CFO Elliot Maltz said. “The previously disclosed $15.0 million pre-order for Plenity that Ro placed in June provided a boost to our liquidity at the end of the quarter. The additional $25.0 million of proceeds from the previously disclosed private placement of promissory notes in July, as well as the committed equity financing agreement with B. Riley we entered into in August that provides us the option to issue up to $50.0 million of common stock, further strengthens our financial position.” Key Business Metrics For the Three Months Ended June 30, For the Six Months Ended June 30, 2022 2021 2022 2021 In thousands (Unaudited) (Unaudited) (Unaudited) (Unaudited) New members acquired 43,800 14,200 84,200 28,300 Units sold 129,890 33,120 244,460 81,881 Product revenue, net $ 8,973 $ 2,178 $ 16,487 $ 5,279 Average selling price per unit, net $ 69.08 $ 65.76 $ 67.44 $ 64.47 Gross profit $ 4,187 $ 173 $ 6,788 $ 458 Gross margin 47 % 8 % 41 % 9 % Second Quarter 2022 Results Product revenue, net, was $9.0 million for the second quarter 2022 compared to $2.2 million for the second quarter 2021, a 312% increase year-over-year. A total of 43,800 members joined during second quarter 2022 compared to 14,200 members joined during the second quarter 2021, a 208% increase year-over-year. Gross profit was $4.2 million for the second quarter 2022 compared to $0.2 million for the second quarter 2021, with gross margin for the second quarter 2022 increasing to 47% from 8% in the second quarter 2021, attributable to increased sales volume and lower costs of goods sold. Net loss for the quarter was $(12.5) million and Adjusted EBITDA was $(24.2) million for the second quarter 2022, compared to net loss of $(24.8) million and adjusted EBITDA of $(16.6) million for the second quarter 2021. A reconciliation of Adjusted EBITDA, a non-GAAP financial measure, to net loss, its most comparable financial measure under generally accepted accounting principles in the United States (“U.S. GAAP”), is included in the tables accompanying this press release. See “Non-GAAP Financial Measures” for additional important information regarding Adjusted EBITDA. Recent Business Highlights Following the successful debut of the national broad awareness media campaign during the first quarter 2022, which resulted in a new record high for prescription requests, in June, the Company’s telehealth distribution partner, Ro, placed an additional pre-order for $15.0 million. This is in addition to previous Plenity pre-orders from Ro, bringing total fully pre-paid orders from Ro for Plenity to $55.0 million. Gelesis presented new preclinical data at the American Diabetes Association’s annual conference that suggests that the company’s superabsorbent hydrogel causes changes to the microbiota leading to weight loss and improvements in glucose tolerance and insulin sensitivity. In July, Gelesis completed a private placement of $25.0 million in promissory notes with existing top tier investors. In August, Gelesis entered into a committed equity financing agreement with B. Riley Principal Capital II, LLC, providing increased financial flexibility by allowing the company the option to issue up to $50.0 million of common stock. Any issuance activity under this facility will be undertaken opportunistically as market conditions warrant and with the interests of shareholders at the forefront. Financial Outlook for Fiscal Year 2022 Gelesis is confident in the strong long-term potential of Plenity, while our financial projections have always been contingent on the timing and amount of raising additional financing. Based on current market conditions, available liquidity, and in anticipation of reduced levels of investment in selling and marketing in the second half of 2022 relative to the first half, Gelesis is updating its guidance for the full fiscal year 2022 as follows: Product revenue, net, to be in the range of $27.0 million to $30.0 million, compared to an estimate of $58.0 million previously. Gross profit to be in the range of $11.0 million to $13.0 million, compared to a range of $25.0 million to $30.0 million previously. Adjusted EBITDA to be in the range of $(75.0) million to $(80.0) million, compared to a range of $(55.0) million to $(60.0) million previously. The guidance provided above constitutes forward-looking statements which are subject to uncertainty. Actual results may differ materially, and we cannot anticipate the effect of changes in marketing investment on our results from operations. Refer to the "Forward-Looking Statements" safe harbor section below for information on the factors that could cause our actual results to differ materially from these forward-looking statements. Conference Call and Webcast Information Gelesis management will host a conference call today at 8:30 am ET to discuss the second quarter 2022 results, followed by a question-and-answer period. The live call can be accessed via webcast on the “Events & Presentations” section of the Gelesis Investor Relations website at https://ir.gelesis.com/. The webcast will also be archived and available for replay shortly after the call has concluded. Those who are interested in participating in the live call can dial 844-200-6205 from the U.S. and 929-526-1599 internationally and enter the access code 398940. About Gelesis Gelesis Holdings Inc. (NYSE: GLS) (“Gelesis”) is a consumer-centered biotherapeutics company and the maker of Plenity®, which is inspired by nature and FDA cleared to aid in weight management. Our first-of-their-kind non-systemic superabsorbent hydrogels are made entirely from naturally derived building blocks. They are inspired by the composition and mechanical properties of raw vegetables, taken by capsule, and act locally in the digestive system, so people feel satisfied with smaller portions. Our portfolio includes Plenity® and potential therapies in development for patients with Type 2 Diabetes, Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH), and Functional Constipation. For more information, visit gelesis.com, or connect with us on Twitter @GelesisInc. Plenity® is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 25–40 kg/m², when used in conjunction with diet and exercise. Important Safety Information about Plenity Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. For all medications that should be taken without food (on an empty stomach), continue taking on an empty stomach or as recommended by your physician. For all medications that should be taken with food, take them after starting a meal. For all medications that should be taken without food (on an empty stomach), continue taking on an empty stomach or as recommended by your physician. The overall incidence of side effects with Plenity was no different than placebo. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Contact a doctor right away if problems occur. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. Rx Only. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY. Forward-Looking Statements Certain statements, estimates, targets and projections in this press release may constitute “forward-looking statements” within the meaning of the federal securities laws. The words “anticipate,” “believe,” continue,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “strive,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that statement is not forward looking. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Forward-looking statements include, but are not limited to, statements regarding Gelesis’ or its management team’s expectations, hopes, beliefs, intentions or strategies regarding the future, including those relating to Gelesis’ expected operating and financial performance and market opportunities. In addition, any statements that refer to projections, forecasts, or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and Gelesis assumes no obligation and does not intend to update or revise these forward-looking statements, whether as a result of new information, future events, or otherwise. Gelesis gives no assurance that any expectations set forth in this press release will be achieved. Various risks and uncertainties (some of which are beyond Gelesis’ control) or other factors could cause actual future results, performance or events to differ materially from those described herein. Some of the factors that may impact future results and performance may include, without limitation: (i) the ability of Gelesis to raise financing, if and when needed; (ii) the ability of Gelesis to continue as a going concern; (iii) Gelesis’ ability to achieve and maintain widespread market acceptance of Plenity; (iv) the impact of current and future applicable laws and regulations and Gelesis’ ability to comply with such laws and regulations; (v) Gelesis’ ability to produce adequate supply of Plenity, including Gelesis’ ability to continue to invest in manufacturing capacity and to build additional manufacturing sites; (vi) the development of the telehealth market and regulations related to remote healthcare; (vii) global economic, political and social conditions and uncertainties in the markets that Gelesis serves, including risks and uncertainties caused by the COVID-19 pandemic or other natural or man-made disasters; (viii) Gelesis' ability to enter into strategic collaborations, to acquire businesses or products or form strategic alliances and to realize the benefits of such collaborations, acquisitions and alliances; (ix) the level of demand, and willingness of potential members to pay out-of-pocket for, Plenity; (x) the ability of Gelesis to enforce its intellectual property rights and proprietary technology ; (xi) the risk that a third-party’s activities, including with respect to third parties that Gelesis has granted out licenses to or granted limited exclusive or non-exclusive commercial rights, may overlap or interfere with the commercialization of Plenity; (xii) Gelesis’ ability to successfully develop and expand its operations and manufacturing and to effectively manage such growth; (xiii) Gelesis’ business partners' ability to successfully launch and commercialize Plenity in certain key markets; (xiv) risk relating to the loss of Gelesis’ suppliers or distributors, or their inability to provide adequate supply of materials or distribution; (xv) the risk that Gelesis’ business partners may experience significant disruptions in their operations; (xvi) Gelesis’ ability to retain its senior executive officers and to attract and keep senior management and key scientific and commercial personnel; (xvii) Gelesis’ ability to identify and discover additional product candidates and to obtain and maintain regulatory approval for such candidates; (xviii) risks related to potential product liability exposure for Plenity or other future product candidates; (xix) risks related to adverse publicity in the weight management industry, changes in the perception of Gelesis’ brands, and the impact of negative information or inaccurate information about Gelesis on social media; (xx) Gelesis’ ability to enhance its brand recognition, increase distribution of Plenity and generate product sales and reduce operating losses going forward; (xxi) the impact of risks associated with economic, financial, political, environmental and social matters and conditions on Gelesis’ supply chain, its manufacturing operations and other aspects of its business; (xxii) Gelesis’ ability to accurately forecast revenue and appropriately monitor its associated expenses in the future; (xxiii) Gelesis’ ability to compete against other weight management and wellness industry participants or other more effective or more favorably perceived weight management methods, including pharmaceuticals, devices and surgical procedures; (xxiv) foreign currency fluctuations and inflation; (xxv) the risk that Gelesis fails to maintain adequate operational and financial resources or to raise additional capital or generate sufficient cash flows; (xxvi) Gelesis’ ability to successfully protect against security breaches and other disruptions to its information technology structure; (xxvii) the ability of Gelesis to maintain its listing on the New York Stock Exchange; (xxviii) failure to realize the anticipated benefits of the business combination; and (xxix) other important factors discussed in the “Risk Factors” section of Gelesis’ most recent Annual Report on Form 10-K and in other filings that Gelesis makes with the Securities and Exchange Commission. These filings address other important risks and uncertainties that could cause actual results and events to differ materially from those contained in the forward-looking statements. Disclaimer Gelesis assumes no obligation and does not intend to update or revise the results provided in this press release. The results provided in this press release represent past performance and are not necessarily predictive of future results. Key Business Metrics We monitor the following key metrics to help us evaluate our business, identify trends affecting our business, formulate business plans and make strategic decisions. We believe the following metrics are useful in evaluating our business: New members acquired We define new members acquired as the number of consumers in the United States who have begun their weight loss journey with Plenity during the financial period presented. This is the total number of recurring and non-recurring consumers who have begun their weight loss journey during the financial period presented. We do not differentiate from recurring and non-recurring consumers as of this date as (i) we strongly believe every member’s weight-loss journey is chronic and long-term in nature, and (ii) we have not initiated our long-term strategy and mechanisms to retain and/or win-back members. We will continue to evaluate the utility of this business metric in future periods. Units sold Units sold is defined as the number of 28-day supply units of Plenity sold through strategic partnerships with online pharmacies and telehealth providers as well as the units sold to our strategic partners outside the United States. Note that the terms “units” and “monthly kits”, as mentioned in Gelesis’ various public disclosures and filings, are synonymous when used to describe the sales volume of Plenity. Product revenue, net We recognize product revenue in accordance with Accounting Standards Codification Topic 606, Revenue from Contracts with Customers, when we transfer promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. Our product revenue is derived from product sales of Plenity, net of estimates of variable consideration for which reserves are established for expected product returns, shipping charges to end-users, pharmacy dispensing and platform fees, merchant and processing fees, and promotional discounts offered to end-users. Average selling price per unit, net Average selling price per unit, net is the gross price per unit sold during the period net of estimates of per unit variable consideration for which reserves are established for expected product returns, shipping charges to end-users, pharmacy dispensing and platform fees, merchant and processing fees, and promotional discounts offered to end-users. Gross profit and gross margin Our gross profit represents product revenue, net, less our total cost of goods sold, and our gross margin is our gross profit expressed as a percentage of our product revenue, net. Our gross profit and gross margin have been and will continue to be affected by a number of factors, including the prices we charge for our product, the costs we incur from our vendors for certain components of our cost of goods sold, the mix of channel sales in a period, and our ability to sell our inventory. Non-GAAP Financial Measures In addition to our financial results determined in accordance with GAAP, we believe that Adjusted EBITDA, a non-GAAP measure, is useful in evaluating our operating performance. We define “Adjusted EBITDA” as net (loss) income before depreciation and amortization expenses, provision for (benefit from) income taxes, interest expense, net, stock-based compensation and (gains) and losses related to changes in fair value of our warrant liability, our convertible promissory note liability, our tranche rights liability and the One S.r.l. call option. We use Adjusted EBITDA to evaluate our ongoing operations and for internal planning and forecasting purposes because it facilitates internal comparisons of our historical operating performance. We believe that this non-GAAP financial measure, when taken together with the corresponding GAAP financial measure, net loss, provides meaningful supplemental information regarding our performance by excluding certain items that may not be indicative of our business, results of operations, or outlook. We consider Adjusted EBITDA to be an important measure because it helps illustrate underlying trends in our business and our historical operating performance on a more consistent basis. We believe that Adjusted EBITDA is helpful to our investors as it is a metric used by management in assessing the health of our business and our operating performance. However, non-GAAP financial information is presented for supplemental informational purposes only, has limitations as an analytical tool and should not be considered in isolation or as a substitute for financial information presented in accordance with GAAP. In addition, other companies, including companies in our industry, may calculate similarly titled non-GAAP financial measures differently or may use other measures to evaluate their performance, all of which could reduce the usefulness of Adjusted EBITDA as a tool for comparison. A reconciliation is provided below for Adjusted EBITDA to the most directly comparable financial measure stated in accordance with GAAP. Investors are encouraged to review the related GAAP financial measure and the reconciliation of this non-GAAP financial measure to its most directly comparable GAAP financial measure, and not to rely on any single financial measure to evaluate our business. SELECTED UNAUDITED CONDENSED CONSOLIDATED BALANCE SHEETS (In thousands) June 30, December 31, 2022 2021 ASSETS Cash and cash equivalents $ 25,341 $ 28,397 Accounts receivable and grants receivable 10,736 9,903 Inventories 18,821 13,503 Property and equipment, net 56,305 58,515 All other current and non-current assets 27,766 35,983 Total assets $ 138,969 $ 146,301 LIABILITIES, REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ EQUITY (DEFICIT) Accounts payable $ 22,135 $ 10,066 Accrued expenses and other current liabilities 9,715 13,660 Deferred income, current portion 33,702 32,370 Notes and convertible notes payable, current portion 3,177 29,078 Warrant liabilities 1,130 15,821 Earnout liability 6,190 — Deferred income, non-current portion 9,040 8,914 Notes payable, non-current portion 30,015 35,131 All other current and non-current liabilities 7,680 7,648 Total liabilities 122,784 152,688 Noncontrolling interest 11,087 11,855 Redeemable convertible preferred stock — 311,594 Total stockholders’ equity (deficit) 5,098 (329,836 ) Total liabilities, noncontrolling interest, redeemable convertible preferred stock and stockholders’ equity (deficit) $ 138,969 $ 146,301 UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (In thousands) For the Three Months Ended June 30, For the Six Months Ended June 30, 2022 2021 2022 2021 Revenue: Product revenue, net $ 8,973 $ 2,178 $ 16,487 $ 5,279 Total revenue, net 8,973 2,178 16,487 5,279 Operating expenses: Costs of goods sold 4,786 2,005 9,699 4,821 Selling, general and administrative 32,450 13,972 70,156 25,917 Research and development 5,523 5,592 12,933 9,968 Amortization of intangible assets 566 566 1,133 1,133 Total operating expenses 43,325 22,135 93,921 41,839 Loss from operations (34,352 ) (19,957 ) (77,434 ) (36,560 ) Change in the fair value of earnout liability 18,812 — 52,681 — Change in the fair value of convertible promissory notes — — (156 ) — Change in the fair value of warrants 2,600 (4,977 ) 6,084 (7,051 ) Interest expense, net (186 ) (227 ) (321 ) (588 ) Other income, net 613 422 930 891 Loss before income taxes (12,513 ) (24,739 ) (18,216 ) (43,308 ) Provision for income taxes — — — 17 Net loss (12,513 ) (24,739 ) (18,216 ) (43,325 ) Accretion of Legacy Gelesis senior preferred stock to redemption value — (82,365 ) (37,934 ) (116,126 ) Accretion of noncontrolling interest put option to redemption value (85 ) (96 ) (173 ) (190 ) Net loss attributable to common stockholders $ (12,598 ) $ (107,200 ) $ (56,323 ) $ (159,641 ) Net loss per share attributable to common stockholders—basic and diluted $ (0.17 ) $ (19.18 ) $ (0.83 ) $ (28.54 ) Weighted average common shares outstanding—basic and diluted 72,423,043 5,589,728 67,609,838 5,592,911 UNAUDITED CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (In thousands) For the Six Months Ended June 30, 2022 2021 Cash flows from operating activities: Net loss $ (18,216 ) $ (43,325 ) Adjustments to reconcile net loss to net cash used in operating activities: . Amortization of intangible assets 1,133 1,133 Reduction in carrying amount of right-of-use assets 265 150 Depreciation 1,440 358 Stock-based compensation 21,965 3,094 Unrealized loss (gain) on foreign currency transactions 672 (28 ) Non-cash interest (income) expense (3 ) 36 Accretion on marketable securities — (1 ) Change in the fair value of earnout liability (52,681 ) — Change in the fair value of warrants (6,084 ) 7,051 Change in the fair value of convertible promissory notes 156 — Change in fair value of One S.r.l. call option 865 554 Changes in operating assets and liabilities: Account receivables (1,473 ) 640 Grants receivable (1,078 ) (675 ) Prepaid expenses and other current assets 5,048 (7,685 ) Inventories (5,258 ) (156 ) Other assets (536 ) (3,281 ) Accounts payable 11,486 (2,374 ) Accrued expenses and other current liabilities 571 8,211 Operating lease liabilities (263 ) (144 ) Deferred income 2,300 7,048 Other long-term liabilities (81 ) (5,975 ) Net cash used in operating activities (39,772 ) (35,369 ) Cash flows from investing activities: Purchases of property and equipment (5,067 ) (10,057 ) Maturities of marketable securities — 24,000 Net cash (used in) provided by investing activities (5,067 ) 13,943 Cash flows from financing activities: Proceeds from Business Combination, net of transaction costs 70,478 — Principal repayment of notes payable (1,119 ) (226 ) Repayment of convertible promissory notes due to related party, held at fair value (27,284 ) — Proceeds from issuance of promissory notes — 4,540 Proceeds from the exercise of warrants 4 9 Proceeds from exercise of share-based awards 110 10 Net cash provided by financing activities 42,189 4,333 Effect of exchange rates on cash (406 ) (680 ) Net decrease in cash (3,056 ) (17,773 ) Cash and cash equivalents at beginning of year 28,397 48,144 Cash and cash equivalents at end of period $ 25,341 $ 30,371 Noncash investing and financing activities: Purchases of property and equipment included in accounts payable and accrued expense $ 1,027 $ 1,217 Deferred financing costs included in accounts payable and accrued expense — $ 506 Recognition of earnout liability $ 58,871 — Recognition of private placement warrant liability $ 8,140 — Supplemental cash flow information: Interest paid on notes payable $ 181 $ 158 NET LOSS TO ADJUSTED EBITDA RECONCILIATION (In thousands, Unaudited) For the Three Months Ended June 30, For the Six Months Ended June 30, 2022 2021 2022 2021 In thousands (Unaudited) (Unaudited) (Unaudited) (Unaudited) Adjusted EBITDA Net loss $ (12,513 ) $ (24,739 ) $ (18,216 ) $ (43,325 ) Provision for income taxes — — — 17 Depreciation and amortization 987 750 2,573 1,491 Stock based compensation expense 7,976 1,639 21,965 3,094 Change in fair value of earnout liability (18,812 ) — (52,681 ) — Change in fair value of warrants (2,600 ) 4,977 (6,084 ) 7,051 Change in fair value of convertible promissory notes — — 156 — Change in fair value of One S.r.l. call option 607 506 865 554 Interest expense, net 186 227 321 588 Adjusted EBITDA $ (24,169 ) $ (16,640 ) $ (51,101 ) $ (30,530 )
  • 08/15/2022

Gelesis Holdings' (GLS) CEO Yishai Zohar on Q1 2022 Results - Earnings Call Transcript

  • Gelesis Holdings, Inc. (NYSE:GLS ) Q1 2022 Earnings Conference Call May 1, 2022 4:30 PM ET Company Participants Yishai Zohar – Founder and Chief Executive Officer Elliot Maltz – Chief Financial Officer David Pass – Chief Operating and Commercial Officer Conference Call Participants Ellie Merle – UBS Operator Good afternoon, everyone, and thank you for participating in today's conference call to discuss Gelesis' financial results for the fiscal quarter ended March 31, 2022. Joining us today are Yishai Zohar, Founder and CEO of Gelesis; and Elliot Maltz, CFO of Gelesis.
  • 05/14/2022

Gelesis to Report First Quarter 2022 Financial Results on May 12, 2022

  • BOSTON--(BUSINESS WIRE)--Gelesis (NYSE: GLS), the maker of Plenity® for weight management, today announced that the Company will report financial results for the First Quarter ended March 31, 2022, on May 12, 2022 following the market close. Gelesis management will host a live conference call and webcast at 4:30 p.m. ET on the same day to discuss the results. Conference Call Details Date: Thursday, May 12, 2022 Time: 4:30 p.m. Eastern Time Toll-free dial-in number: (844) 200-6205 International
  • 05/09/2022

Gelesis Holdings: Advancing Biomimetic Superabsorbent Hydrogels For GI-Related Diseases

  • Gelesis Holdings is the developer of proprietary biomimetic superabsorbent hydrogels for weight loss. The Company is evaluating and investigating its technology in GI-related diseases.
  • 04/19/2022

Gelesis Holdings, Inc. (GLS) CEO Yishai Zohar on Q4 2021 Results - Earnings Call Transcript

  • Gelesis Holdings, Inc. (GLS) CEO Yishai Zohar on Q4 2021 Results - Earnings Call Transcript
  • 03/24/2022

Gelesis® Reports Fiscal Year 2021 Results and Fiscal Year 2022 Financial Outlook

  • BOSTON--(BUSINESS WIRE)--Gelesis (NYSE: GLS), the maker of Plenity for weight management, today reported financial results for its fiscal year ended December 31, 2021. Yishai Zohar, Founder and CEO of Gelesis, commented, “Earlier this year, we kicked off our debut media campaign for Plenity and have already seen 3.5-fold growth in new Plenity prescriptions in the first few weeks since we began advertising. Demand through both our telehealth and our traditional healthcare provider channels has quickly reached record highs. We are thrilled by the feedback we are receiving from thousands of new members who have recently begun their weight loss journey with Plenity.” As previously reported, Gelesis raised $105 million in gross proceeds upon completion of a business combination with Capstar Special Purpose Acquisition Corp. on January 13, 2022, debuting the following day as a publicly traded company on the New York Stock Exchange under the ticker symbol “GLS.” Gelesis CFO Elliot Maltz said, “We began investing in broad awareness media in 2022, instead of the fall of 2021, which has shifted some of our projections out by a few months, but our market opportunity remains the same. Already we have seen incredible demand for Plenity, and we are confidently on the path to achieve 400% growth in product revenue by the end of the year while significantly improving our gross margin.” Key Business Metrics (Dollar amounts in thousands except where noted, Unaudited) Year Ended December 31, 2021 2020 Members 79,100 18,800 Units Sold 170,969 40,987 Total product revenue, net $ 11,185 $ 2,708 Average selling price per unit, net $ 65.42 $ 66.07 Gross profit $ 1,202 $ 294 Gross margin 10.7 % 10.9 % Fiscal Year 2021 Results Product revenue, net, for the year was $11.2 million, a 313% increase from 2020 when Plenity first became commercially available through a beta launch. Gelesis received an aggregate $40 million of fully paid preorders for Plenity during 2021. Gross profit for the year was $1.2 million driven primarily by increased sales volume. Net loss for the year was $(93.3) million while Adjusted EBITDA for the year was $(73.8) million. A total of 79,100 members had started their weight management journey with Plenity as of the end of the year, despite limited marketing investment and no efforts for broad awareness building. A reconciliation of Adjusted EBITDA, a non-GAAP financial measure, to net loss, its most comparable financial measure under generally accepted accounting principles in the United States (“U.S. GAAP”), is included in the tables accompanying this press release. See “Non-GAAP Financial Measures” for additional important information regarding Adjusted EBITDA. Recent Business Highlights As recently reported, new Plenity members per day increased 3.5-fold in the first three weeks of the national media campaign launch that kicked off January 31, 2022, compared to previous months before media campaign launch. Following the success of this first wave of the campaign, the company is evaluating optimal media channels, timing, pulse frequency, and investment levels going forward. Gelesis’ exclusive telehealth partner, Ro, responded to growing patient demand when it placed $40 million in pre-orders for Plenity last year. Since then, the broad consumer launch, as well as the continued growth of Ro’s direct-to-patient healthcare platform, has led to Plenity becoming one of the most sought-after offerings on Ro’s platform and bringing in more new members than any other product. Healthcare provider (“HCP”) prescribing of Plenity was up 100% over the first three weeks of the media campaign began, and 40% of HCP prescriptions were requested by the consumer (a 60% increase from the Company’s pre-campaign baseline). Gelesis completed the first phase of building its commercial-scale manufacturing facility at the end of 2021 and ramped-up supply to meet anticipated commercial demand. Completed business combination with Capstar SPAC on January 13, 2022, resulting in gross proceeds of $105 million. Financial Outlook for Fiscal Year 2022 Gelesis provides guidance based on current market conditions and expectations for revenue, gross profit, and Adjusted EBITDA, which is a non-GAAP financial measure. Gelesis estimates product revenue, net, of about $58 million in 2022. Gelesis estimates a gross profit of $25 million to $30 million. Gelesis estimates Adjusted EBITDA of $(55) million to $(60) million. The guidance provided above constitutes forward-looking statements which are subject to uncertainty. Actual results may differ materially and we cannot anticipate the effect of changes in marketing investment on our results from operations. Refer to the “Forward-Looking Statements” safe harbor section below for information on the factors that could cause our actual results to differ materially from these forward-looking statements. Our product revenue, net, gross profit, and Adjusted EBITDA guidance is based on, among other factors, our current expectations regarding the amount and timing of investments in broad awareness media, which could be impacted by available liquidity and other considerations as we monitor the rate of growth in new Plenity members and units sold during upcoming quarters. We have not reconciled forward-looking Adjusted EBITDA to its most directly comparable U.S. GAAP measure, net loss, because we cannot predict with reasonable certainty the ultimate outcome of certain components of such reconciliations, including market-related assumptions that are not within our control, or others that may arise, without unreasonable effort. For these reasons, we are unable to assess the probable significance of the unavailable information, which could materially impact the amount of future net loss. Fiscal Year 2021 Conference Call and Webcast Information Gelesis will host a conference call today at 4:30 pm ET to discuss the fiscal year 2021 results, followed by a question-and-answer period. The conference call can be accessed by dialing +1 (844) 200-6205 for U.S. participants and +1 (929) 526-1599 for all other participants. The conference ID is 649881. A live webcast will also be available here, or on the Company’s investor relations website at https://ir.gelesis.com/. A replay of the webcast will be available shortly afterwards. About Gelesis Gelesis Holdings Inc. (NYSE: GLS) (“Gelesis”) is a consumer-centered biotherapeutics company and the maker of Plenity®, which is inspired by nature and FDA cleared to aid in weight management. Our first-of-their-kind non-systemic superabsorbent hydrogels are made entirely from naturally derived building blocks. They are inspired by the composition and mechanical properties of raw vegetables, taken by capsule, and act locally in the digestive system, so people feel satisfied with smaller portions. Our portfolio includes Plenity® and potential therapies in development for patients with Type 2 Diabetes, Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH), and Functional Constipation. For more information, visit gelesis.com, or connect with us on Twitter @GelesisInc. Plenity® is indicated to aid weight management in adults with excess weight or obesity, a Body Mass Index (BMI) of 25–40 kg/m², when used in conjunction with diet and exercise. Important Safety Information about Plenity Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity. To avoid impact on the absorption of medications: For all medications that should be taken with food, take them after starting a meal. For all medications that should be taken without food (on an empty stomach), continue taking on an empty stomach or as recommended by your physician. For all medications that should be taken with food, take them after starting a meal. For all medications that should be taken without food (on an empty stomach), continue taking on an empty stomach or as recommended by your physician. The overall incidence of side effects with Plenity was no different than placebo. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Contact a doctor right away if problems occur. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. Rx Only. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY. Forward-Looking Statements Certain statements, estimates, targets and projections in this press release may constitute “forward-looking statements” within the meaning of the federal securities laws. The words “anticipate,” “believe,” continue,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “should,” “strive,” “would” and similar expressions may identify forward-looking statements, but the absence of these words does not mean that statement is not forward looking. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Forward-looking statements include, but are not limited to, statements regarding our or our management team’s expectations, hopes, beliefs, intentions or strategies regarding the future, including those relating to Gelesis’ business combination with Capstar Special Purpose Acquisition Corp. (“Capstar”) and its expected benefits, Gelesis’ performance following the business combination, the competitive environment in which Gelesis operates, the expected future operating and financial performance and market opportunities of Gelesis and statements regarding Gelesis’ expectations, hopes, beliefs, intentions or strategies regarding the future. In addition, any statements that refer to projections, forecasts, or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and Gelesis assumes no obligation and does not intend to update or revise these forward-looking statements, whether as a result of new information, future events, or otherwise. Gelesis gives no assurance that any expectations set forth in this press release will be achieved. Various risks and uncertainties (some of which are beyond our control) or other factors could cause actual future results, performance or events to differ materially from those described herein. Some of the factors that may impact future results and performance may include, without limitation: (i) the size, demand and growth potential of the markets for Plenity® and Gelesis’ other product candidates and Gelesis’ ability to serve those markets; (ii) the degree of market acceptance and adoption of Gelesis’ products; (iii) Gelesis’ ability to develop innovative products and compete with other companies engaged in the weight loss industry; (iv) Gelesis’ ability to finance and complete successfully the commercial launch of Plenity® and its growth plans, including new possible indications and the clinical data from ongoing and future studies about liver and other diseases; (v) failure to realize the anticipated benefits of the business combination, including as a result of a delay or difficulty in integrating the businesses of Capstar and Gelesis; (vi) the ability of Gelesis to issue equity or equity-linked securities or obtain debt financing in the future; (vii) the outcome of any legal proceedings instituted against Capstar, Gelesis, or others in connection with the business combination; (viii) the ability of Gelesis to maintain its listing on the New York Stock Exchange; (ix) the risk that the business combination disrupts current plans and operations of Gelesis as a result of Gelesis being a publicly listed issuer; (x) the regulatory pathway for Gelesis’ products and responses from regulators, including the FDA and similar regulators outside of the United States; (xi) the ability of Gelesis to grow and manage growth profitably, maintain relationships with customers and suppliers and retain Gelesis’ management and key employees; (xii) costs related to the business combination, including costs associated with the Gelesis being a publicly listed issuer; (xiii) changes in applicable laws or regulations; (xiv) the possibility that Gelesis may be adversely affected by other economic, business, regulatory and/or competitive factors; (xv) Gelesis’ estimates of expenses and profitability; (xvi) ongoing regulatory requirements, (xvii) any competing products or technologies that may emerge, (xviii) the volatility of the telehealth market in general, or insufficient patient demand; (xix) the ability of Gelesis to defend its intellectual property and satisfy regulatory requirements; (xx) the impact of the COVID 19 pandemic on Gelesis’ business; (xxi) the limited operating history of Gelesis; (xxii) the potential impact of inflation on our operating expenses and costs of goods; and (xxiii) those factors discussed in Capstar’s joint proxy/prospectus filed with the SEC on December 27, 2021, under the heading “Risk Factors”, and other documents of Gelesis filed, or to be filed, with the SEC, by Gelesis. These filings address other important risks and uncertainties that could cause actual results and events to differ materially from those contained in the forward-looking statements. Key Business Metrics We monitor the following key metrics to help us evaluate our business, identify trends affecting our business, formulate business plans and make strategic decisions. We believe the following metrics are useful in evaluating our business: Disclaimer Gelesis assumes no obligation and does not intend to update or revise the results provided in this press release. The results provided in this press release represent past performance and are not necessarily predictive of future results. Members We define members as the number of consumers in the United States who have begun their weight loss journey with Plenity. This is the cumulative historical number of recurring and non-recurring consumers who have begun their weight loss journey as of the respective reporting date. We do not differentiate from recurring and non-recurring consumers as of the date of this earnings release as (i) we strongly believe every member’s weight-loss journey is chronic and long-term in nature, and (ii) owing to a limited available supply of Plenity to-date, we have not initiated our long-term strategy and mechanisms to retain and/or win-back members. Units sold Units sold is defined as the number of 28-day supply units of Plenity sold to consumers based on prescriptions, through our strategic partnerships with online pharmacies and telehealth providers as well as the units sold to our strategic partners outside the United States. Note that the terms “units” and “monthly kits”, as mentioned in Gelesis’ various public disclosures and filings, are synonymous when used to describe the sales volume of Plenity. Product revenue, net We recognize product revenue in accordance with Accounting Standards Codification Topic 606, Revenue from Contracts with Customers, when we transfer promised goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. Our product revenue is derived from product sales of Plenity, net of estimates of variable consideration for which reserves are established for expected product returns, shipping charges to end-users, pharmacy dispensing and platform fees, merchant and processing fees, and promotional discounts offered to end-users. Average selling price per unit, net Average selling price per unit, net is the gross price per unit sold during the period net of estimates of per unit variable consideration for which reserves are established for expected product returns, shipping charges to end-users, pharmacy dispensing and platform fees, merchant and processing fees, and promotional discounts offered to end-users. Gross profit and gross margin Our gross profit represents product revenue, net, less our total cost of goods sold, and our gross margin is our gross profit expressed as a percentage of our product revenue, net. Our gross profit and gross margin have been and will continue to be affected by a number of factors, including the prices we charge for our product, the costs we incur from our vendors for certain components of our cost of goods sold, the mix of channel sales in a period, and our ability to sell our inventory. Non-GAAP Financial Measures In addition to our financial results determined in accordance with GAAP, we believe that Adjusted EBITDA, a non-GAAP measure, is useful in evaluating our operating performance. We define “Adjusted EBITDA” as net (loss) income before depreciation and amortization expenses, provision for (benefit from) income taxes, interest expense, net, stock-based compensation and (gains) and losses related to changes in fair value of our warrant liability, our convertible promissory note liability, our tranche rights liability and the One S.r.l. call option. We use Adjusted EBITDA to evaluate our ongoing operations and for internal planning and forecasting purposes because it facilitates internal comparisons of our historical operating performance. We believe that this non-GAAP financial measure, when taken together with the corresponding GAAP financial measure, net loss, provides meaningful supplemental information regarding our performance by excluding certain items that may not be indicative of our business, results of operations, or outlook. We consider Adjusted EBITDA to be an important measure because it helps illustrate underlying trends in our business and our historical operating performance on a more consistent basis. We believe that Adjusted EBITDA is helpful to our investors as it is a metric used by management in assessing the health of our business and our operating performance. However, non-GAAP financial information is presented for supplemental informational purposes only, has limitations as an analytical tool and should not be considered in isolation or as a substitute for financial information presented in accordance with GAAP. In addition, other companies, including companies in our industry, may calculate similarly-titled non-GAAP financial measures differently or may use other measures to evaluate their performance, all of which could reduce the usefulness of Adjusted EBITDA as a tool for comparison. A reconciliation is provided below for Adjusted EBITDA to the most directly comparable financial measure stated in accordance with GAAP. Investors are encouraged to review the related GAAP financial measure and the reconciliation of this non-GAAP financial measure to its most directly comparable GAAP financial measure, and not to rely on any single financial measure to evaluate our business. SELECTED CONSOLIDATED BALANCE SHEETS (In thousands, Unaudited) December 31, 2021 2020 ASSETS Cash, cash equivalents and marketable securities $ 28,397 $ 72,142 Accounts receivable and grants receivable 9,903 8,934 Inventories 13,406 5,122 Property and equipment, net 58,515 46,895 All other current and non-current assets 36,080 30,750 Total assets $ 146,301 $ 163,843 LIABILITIES, REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ DEFICIT Accounts payable $ 10,066 $ 8,322 Accrued expenses and other current liabilities 13,670 7,320 Deferred income, current portion 32,351 624 Notes and convertible notes payable, current portion 29,078 254 Deferred income, non-current portion 8,914 8,276 Notes payable, non-current portion 35,131 34,002 All other current and non-current liabilities 23,478 26,029 Total liabilities 152,688 84,827 Noncontrolling interest 11,855 12,429 Redeemable convertible preferred stock 311,594 213,525 Total stockholders’ deficit (329,836 ) (146,938 ) Total liabilities, noncontrolling interest, redeemable convertible preferred stock and stockholders’ deficit $ 146,301 $ 163,843 CONSOLIDATED STATEMENTS OF OPERATIONS (In thousands, Unaudited) Year Ended December 31, 2021 2020 Revenue: Product revenue, net $ 11,185 $ 2,708 Licensing revenue — 18,734 Total revenue, net 11,185 21,442 Operating expenses: Costs of goods sold 9,983 2,414 Selling, general and administrative 71,041 28,870 Research and development, 12,867 16,115 Amortization of intangible assets 2,267 2,267 Total operating expenses 96,158 49,666 Loss from operations (84,973 ) (28,224 ) Change in the fair value of convertible promissory notes (128 ) — Change in the fair value of warrants (7,646 ) (1,466 ) Change in fair value of tranche rights liability — 256 Interest expense, net (1,364 ) (432 ) Other income, net 781 6,000 Loss before income taxes (93,330 ) (23,866 ) Provision for income taxes 17 2,039 Net loss (93,347 ) (25,905 ) Accretion of senior preferred stock to redemption value (94,134 ) (11,372 ) Accretion of noncontrolling interest put option to redemption value (376 ) (567 ) Net loss attributable to common stockholders $ (187,857 ) $ (37,844 ) Net loss per share attributable to common stockholders—basic and diluted $ (85.22 ) $ (17.61 ) Weighted average common shares outstanding—basic and diluted 2,204,486 2,149,182 CONSOLIDATED STATEMENTS OF CASH FLOWS (In thousands, Unaudited) Year ended December 31, 2021 2020 Cash flows from operating activities: Net loss $ (93,347 ) $ (25,905 ) Adjustments to reconcile net loss to net cash used in operating activities: . Amortization of intangible assets 2,267 2,267 Reduction in carrying amount of right-of-use assets 449 375 Depreciation 1,524 512 Stock-based compensation 5,532 4,808 Unrealized loss on foreign currency transactions (37 ) (589 ) Noncash interest expense 173 — Accretion on marketable securities (1 ) (6 ) Amortization/accretion on long-term assets and liabilities, net — (4 ) Change in the fair value of warrants 7,646 1,466 Change in the fair value of convertible promissory notes 128 — Change in fair value of One S.r.l. call option 1,024 — Gain on extinguishment of debt — (297 ) Gain on extinguishment of preferred stock warrant — (157 ) Change in fair value of trance rights liability — (256 ) Deferred tax expense on intangible asset — 1,810 Changes in operating assets and liabilities: Account receivables 70 (729 ) Grants receivable (1,723 ) (6,779 ) Prepaid expenses and other current assets (8,029 ) (3,281 ) Inventories (8,645 ) (3,928 ) Other assets 107 (3,583 ) Accounts payable 2,604 4,085 Accrued expenses and other current liabilities 8,709 151 Operating lease liabilities (440 ) (358 ) Deferred income 33,140 8,242 Other long-term liabilities (6,442 ) 165 Net cash used in operating activities (55,291 ) (21,991 ) Cash flows from investing activities: Purchases of property and equipment (19,917 ) (32,212 ) Maturities (purchases) of marketable securities 24,000 (23,993 ) Net cash provided by (used) in investing activities 4,083 (56,205 ) Cash flows from financing activities: Principal repayment of notes payable (302 ) (192 ) Proceeds from the exercise of warrants 10 — Proceeds from the issuance of convertible promissory notes 27,000 — Proceeds from issuance of promissory notes (net of issuance costs of $207 and $751, respectively) 5,679 28,939 Proceeds from issuance of redeemable convertible preferred stock (net of issuance costs of $0 and $329, respectively) — 48,815 Proceeds from exercise of share-based awards 146 12 Proceeds from issuance of noncontrolling interest — 11,349 Net cash provided by financing activities 32,533 88,923 Effect of exchange rates on cash (1,072 ) 1,643 Net decrease (increase) in cash (19,747 ) 12,370 Cash and cash equivalents at beginning of year 48,144 35,774 Cash and cash equivalents at end of year $ 28,397 $ 48,144 Noncash investing and financing activities: Purchases of property and equipment included in accounts payable and accrued expense $ 1,712 $ 1,818 Deferred financing costs included in accounts payable and accrued expense $ 773 $ — Supplemental cash flow information: Lease liabilities arising from obtaining right-of-use assets $ 305 $ — Interest paid on notes payable $ 1,578 $ 274 Net Loss to Adjusted EBITDA Reconciliation (In thousands, Unaudited) Year Ended December 31, 2021 2020 Adjusted EBITDA Net loss $ (93,347 ) $ (25,905 ) Provision for (benefit from) income taxes 17 2,039 Amortization and depreciation 3,791 2,779 Stock based compensation expense 5,532 4,808 Change in fair value of warrants 7,646 1,466 Change in fair value of convertible promissory notes 128 — Change in fair value of tranche rights liability — (256 ) Change in fair value of One S.r.l. call option 1,024 — Interest expense, net 1,364 432 Adjusted EBITDA $ (73,845 ) $ (14,637 )
  • 03/24/2022

Gelesis to Report Full Year 2021 Financial Results on March 24, 2022

  • BOSTON--(BUSINESS WIRE)---- $GLS #earnings--Gelesis (NYSE: GLS), the maker of Plenity® for weight management, today announced that the Company will report financial results for fiscal year 2021 on March 24, 2022, following the market close. Gelesis management will host a live conference call and webcast at 4:30 p.m. ET on the same day to discuss the results. The live conference call webcast can be accessed on the Gelesis Investor Relations website at https://ir.gelesis.com/. The webcast will also be archived and
  • 03/17/2022
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