Profile
SION VRTX REGN VRNA ARGX ALNY
Company Name Sionna Therapeutics, Inc. Vertex Pharmaceuticals Incorporated Regeneron Pharmaceuticals, Inc. Verona Pharma plc argenx SE Alnylam Pharmaceuticals, Inc.
Sector Healthcare Healthcare Healthcare Healthcare Healthcare Healthcare
Industry Biotechnology Biotechnology Biotechnology Biotechnology Biotechnology Biotechnology
Market Cap $1.63B $122.53B $81.62B $72.68B $50.22B $43.35B
Employees 0.04K 6.10K 15.16K 0.21K 1.60K 2.23K
CEO Michael Cloonan Reshma Kewalramani Leonard S. Schleifer David S. Zaccardelli Timothy Van Hauwermeiren Yvonne L. Greenstreet
Ratings
SION VRTX REGN VRNA ARGX ALNY
Quant Rating Score 2 4 4 1 4 3
Quant Rating Sell Buy Buy Strong Sell Buy Neutral
Trading
SION VRTX REGN VRNA ARGX ALNY
Last Close $39.93 $434.02 $704.31 $106.91 $929.61 $460.54
High 52 $42.58 $513.76 $788 $106.91 $929.61 $491.09
Low 52 - $366.54 $482.92 $37.86 $532.27 $224.58
Price vs. 52 Week High -6.22 % -15.52 % -10.62 % 0 % 0 % -6.22 %
Price vs. 52 Week Low 0 % 18.41 % 45.84 % 182.38 % 74.65 % 105.07 %
Total Return
SION VRTX REGN VRNA ARGX ALNY
1 Month Return 25.05 % 4.13 % 21.84 % 0 % 10.19 % -4.39 %
3 Month Return 86.68 % 11.32 % 22.74 % 1.06 % 40.57 % 0.8 %
6 Month Return 197.32 % -1.06 % 18.51 % 49.92 % 64.35 % 61.42 %
9 Month Return 98.56 % -6.08 % 3.57 % 66.4 % 45.48 % 84.22 %
YTD Return 0 % 7.78 % -1.13 % 130.21 % 51.16 % 95.72 %
1 Year Return 0 % -3.12 % -5.41 % 180.68 % 61.8 % 96.59 %
3 Year Return 0 % 0 % 0 % 0 % 0 % 0 %
5 Year Return 0 % 0 % 0 % 0 % 0 % 0 %
Dividends
SION VRTX REGN VRNA ARGX ALNY
Dividend Yield Percentage (TTM) - - 0.45 % - - -
Dividend Paid and Capex Coverage Ration (TTM) -355.21 % 9.76 % 3.92 % -147.93 % 65.28 % 5.97 %
Dividend Per Share (TTM) - - 3.52 % - - -
Payout Ratio (TTM) - - 8.22 % - - -
Growth
SION VRTX REGN VRNA ARGX ALNY
Asset Growth 257.59 % 7.41 % 53.91 % 10.71 %
Gross Profit Growth - 1.16 % - 26.81 %
Revenue Growth - 0.99 % - 22.97 %
Revenue 3 Year - 20.64 % -15.89 % 147.1 %
Revenue 5 Year - 73.64 % - 775.72 %
Revenue 10 Year - 285.02 % - 2487.4 %
EBIT Growth -40.18 % 9.09 % -131.37 % 24.59 %
Net Income Growth -30.52 % 2.09 % -224.78 % 36.82 %
Net Income 3 Yeari Growth Per Share -53.3 % 6.32 % -148.34 % 69.73 %
Net Income 5 Yeari Growth Per Share -53.3 % 31.91 % 25.82 % 73.13 %
Net Income 10 Yeari Growth Per Share -53.3 % 680.22 % -35.51 % 55.09 %
Operating Income Growth -40.18 % -7.46 % -133.02 % 37.31 %
Operating Cash Flow Growth (CFG) -20.8 % - -143.33 % -107.98 %
Operating 3 Year CFG -46.35 % -100 % -170.73 % 98.8 %
Operating 5 Year CFG -46.35 % -100 % 54.81 % 97.44 %
Operating 10 Year CFG -46.35 % -100 % 40.15 % 97.08 %
EPS Growth -30.71 % 5.31 % -214.81 % 38.07 %
EPS Diluted Growth -30.71 % 8.19 % -208.93 % 38.07 %
Book Value Per Share -42.51 % 32.88 % -22.82 % 129.75 %
Share Holder 3 Year Equity Growth Per Share -134.13 % 41.21 % 1.82 % -89.42 %
Share Holder 5 Year Equity Growth Per Share -134.13 % 191.63 % -24.45 % -96.01 %
Share Holder 10 Year Equity Growth Per Share -134.13 % 842.11 % -71.86 % -95.83 %
Dividend Per Share Growth - - - -
Dividend 3 Year Growth Per Share - - - -
Dividend 5 Year Growth Per Share - - - -
Dividend 10 Year Growth Per Share - - - -
Debt Growth -6.95 % 0.06 % 139.05 % 110.16 %
Free Cash Flow Growth -17.85 % - -144.48 % -201.54 %
Updated On 31 Dec 2024 31 Dec 2025 31 Dec 2024 31 Dec 2024
Profitability
SION VRTX REGN VRNA ARGX ALNY
Gross Profit Margin TTM - 86.28 % 86.27 % 95.15 % 65.82 % 83.99 %
Return on Assets TTM -20.83 % 14.78 % 11.11 % -11.01 % 15.06 % 0.9 %
Return on Equity TTM -33.41 % 21.81 % 14.83 % -30.05 % 18.96 % 26.13 %
Return on Capital Employed TTM -25.35 % 19.59 % 10.3 % -8.31 % 5.04 % 8.03 %
Net Income Per EBT TTM 100 % 82.61 % 86.12 % 111.64 % 237.3 % -136.38 %
EBT Per Ebit TTM 84.64 % 111.4 % 146.19 % 130.36 % 147.38 % -12.07 %
EBIT Per Revenue TTM - 34.06 % 24.95 % -25.86 % 13.47 % 8.25 %
Cash Flow To Debt Ratio TTM -685.24 % 202.64 % 184 % -29.66 % 932.29 % 9.59 %
Receivables Turnover TTM - 6.02 2.5 1.93 1.91 3.33
Payables Turnover TTM 0.17 0.4 2.1 2.37 0.9 4.37
Inventory Turnover TTM - 0.99 0.62 0.94 2.26 6.82
Fixed Asset Turnover TTM - 388.59 % 280.11 % 6536.22 % 5009.77 % 463.12 %
Asset Turnover TTM - 47.15 % 35.36 % 29.27 % 31.97 % 66.16 %
Operating Cash Flow Per Share TTM -1.38 14.55 48.39 -0.85 5.67 2.02
Free Cash Flow Per Share TTM -1.39 13.06 39.66 -0.85 5.58 1.68
Cash Per Share TTM 558.5 % 2459.7 % 8362.68 % 511.43 % 5536.58 % 2072.79 %
Operating Cash Flow Sales Ratio TTM - 31.71 % 34.71 % -43.23 % 17.54 % 8.28 %
Free Cash Flow Operating Cash Flow Ratio TTM 100.33 % 89.76 % 81.96 % 100.75 % 98.47 % 83.26 %
Cash Flow Coverage Ratios TTM -685.24 % 202.64 % 184 % -29.66 % 932.29 % 9.59 %
Price To Free Cash Flows Ratio TTM -26.44 36.72 20 -995.27 127.92 195.85
Price To Operating Cash Flows Ratio TTM -26.43 32.86 16.23 -126.33 144.41 162.25
Price Cash Flow Ratio TTM -26.43 32.86 16.23 -126.33 144.41 162.25
Income Statement (TTM)
SION VRTX REGN VRNA ARGX ALNY
Revenue $0B $11.02B $14.34B $0.03B $2.19B $2.25B
Gross Profit $-0B $9.49B $12.24B $0.03B $1.96B $1.92B
Gross Profit Ratio 0% 86.11% 85.35% 93.89% 89.62% 85.62%
EBITDA $-0.07B $0.49B $5.82B $-0.12B $0.11B $-0.18B
Net Income $-0.06B $-0.54B $4.5B $-0.14B $0.83B $-0.28B
EPS Diluted -1.4 -2.08 41.48 -1.73 12.78 -2.18
Balance Sheet (MRQ)
SION VRTX REGN VRNA ARGX ALNY
Long Term Debt $0.01B $1.66B $2.71B $0.12B $0.03B $2.59B
Total Liabilities $0.35B $6.12B $9.3B $0.27B $0.7B $4.17B
Total Equity $-0.16B $16.41B $31.26B $0.2B $5.5B $0.07B
Total Investments $0.13B $6.65B $15.75B $0.02B $1.93B $1.73B
Total Debt $0.01B $1.75B $2.71B $0.12B $0.04B $2.74B
Total Assets $0.19B $22.53B $40.56B $0.47B $6.2B $4.24B
Cash Flow Statement (TTM)
SION VRTX REGN VRNA ARGX ALNY
Net Income $-0.06B $-0.54B $4.5B $-0.17B $0.83B $-0.28B
Inventory $0B $-0.52B $-0.28B $-0.01B $-0.1B $0.01B
Dividends Paid $0B $0B $-0.37B $0B $0B $0B
Operating Cash Flow $-0.05B $-0.49B $4.98B $-0.12B $-0.08B $-0.01B
Capital Expenditure $-0B $-0.3B $-0.9B $-0B $-0.07B $-0.03B
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ETFs With Exposure to SION
Ticker ETF Name Weight Percentage Price
IWM iShares Russell 2000 ETF 0.02 264.95
VTI Vanguard Total Stock Market Index Fund 0.00158 341.47
XBI SPDR S&P Biotech ETF 0.196237 124.65
IBB iShares Biotechnology ETF 0.08 172.7
SCHB Schwab U.S. Broad Market ETF 0.000720377 26.71
ITOT iShares Core S&P Total U.S. Stock Market ETF 0 151.38
SCHA Schwab U.S. Small-Cap ETF 0.0123623 30.81
IWV iShares Russell 3000 ETF 0 393.91
LABU Direxion Daily S&P Biotech Bull 3X Shares 0.106768 163.41
IWO iShares Russell 2000 Growth ETF 0.04 339.07
BIB ProShares Ultra Nasdaq Biotechnology 0.085622 84.8735
VXF Vanguard Extended Market Index Fund 0.00759 218.1
HDG ProShares Hedge Replication ETF 0.00237514 52.7979
BBC Virtus LifeSci Biotech Clinical Trials ETF 0.68 40.6
UWM ProShares Ultra Russell2000 0.0136747 53.9
VTHR Vanguard Russell 3000 Index Fund 0.00106 305.97
IWC iShares Micro-Cap ETF 0.12 168.25
DWAS Invesco DWA SmallCap Momentum ETF 0.370967 102.096
URTY ProShares UltraPro Russell2000 0.0106736 64.75
VTWV Vanguard Russell 2000 Value Index Fund 0.00021 176.822
ISCB iShares Morningstar Small-Cap ETF 0.01 69.67
OMFS Invesco Russell 2000 Dynamic Multifactor ETF 0.013182 48.18
PTH Invesco DWA Healthcare Momentum ETF 0.73979 48.82
PWS Pacer WealthShield ETF 0.04 33.185
SBIO ALPS Medical Breakthroughs ETF 1.07 50.61
SMMD iShares Russell 2500 ETF 0.01 81.16
VTWG Vanguard Russell 2000 Growth Index Fund 0.04319 247.625
VTWO Vanguard Russell 2000 Index Fund 0.02223 107.11
VETS Pacer Military Times Best Employers ETF 0.04 38.62
XAW.TO iShares Core MSCI All Country World ex Canada Index ETF 0 53.09
XUU.TO iShares Core S&P U.S. Total Market Index ETF 0 68.91
XUH.TO iShares Core S&P U.S. Total Market Index ETF (CAD-Hedged) 0 55.65
XSU.TO iShares U.S. Small Cap Index ETF (CAD-Hedged) 0.02 50.12
VUN.TO Vanguard U.S. Total Market Index ETF 0.00158 126.01
VUS.TO Vanguard U.S. Total Market Index ETF (CAD-hedged) 0.00156 118.61
VITNX Vanguard Institutional Total Stock Market Index Fund Institutional Shares 0.00157 115
VITPX Vanguard Institutional Total Stock Market Index Fund Institutional Plus Shares 0.00157 114.98
VBAIX Vanguard Balanced Index Fund Institutional Shares 0.00101 52.53
VBIAX Vanguard Balanced Index Fund Admiral Shares 0.00101 52.52
VBINX Vanguard Balanced Index Fund Investor Shares 0.00101 52.53
SLT Pacer Salt High truBeta US Market ETF 0.04 39.22
LSLT Pacer Salt Low truBeta US Market ETF 0.04 32
AVUS Avantis U.S. Equity ETF 0 117.46
VGRO.TO Vanguard Growth ETF Portfolio 0.00058 44.38
VIRS Pacer BioThreat Strategy ETF 0.04 40.025
XBAL.TO iShares Core Balanced ETF Portfolio 0 34.33
XCNS.TO iShares Core Conservative Balanced ETF Portfolio 0 25.84
XEQT.TO iShares Core Equity ETF Portfolio 0 41.58
XGRO.TO iShares Core Growth ETF Portfolio 0 36.085
XINC.TO iShares Core Income Balanced ETF Portfolio 0 21.44
VEQT.TO Vanguard All-Equity ETF Portfolio 0.0007 55.86
VBAL.TO Vanguard Balanced ETF Portfolio 0.00043 37.88
VCNS.TO Vanguard Conservative ETF Portfolio 0.00029 32.13
VCIP.TO Vanguard Conservative Income ETF Portfolio 0.00015 27.34
VRIF.TO Vanguard Retirement Income ETF Portfolio 0.00013 26.99
IBBQ Invesco Nasdaq Biotechnology ETF 0.129321 29.4458
2B70.DE iShares Nasdaq US Biotechnology UCITS ETF USD (Acc) 0.13 7.182
VTSAX Vanguard Total Stock Market Index Fund 0.00158 166.24
AVSU Avantis Responsible U.S. Equity ETF 0.01 79.53
BTEC.L iShares Nasdaq US Biotechnology UCITS ETF USD (Acc) 0.13 8.52
SBIO.MI Invesco NASDAQ Biotech UCITS ETF 0.1286 51.22
R2US.L SPDR Russell 2000 US Small Cap UCITS ETF 0.021888 77.17
VIEIX Vanguard Extended Market Index Fund Institutional Shares 0.00759 165.55
VITSX Vanguard Total Stock Market Index Fund 0.00158 166.27
BTEE.L iShares Nasdaq US Biotechnology UCITS ETF 0.13 8.475
XRS2.F Xtrackers Russell 2000 UCITS ETF 0.0164489 318.35
SC0K.DE Invesco Russell 2000 UCITS ETF 0.0195 113.88
SBIO.L Invesco NASDAQ Biotech UCITS ETF 0.1286 60.89
VEXAX Vanguard Extended Market Index Fd Admiral Shs 0.00759 165.56
RTYS.L Invesco Russell 2000 UCITS ETF 0.0195 135.35
XRSG.L Xtrackers (IE) Public Limited Company - Xtrackers Russell 2000 UCITS ETF 0.0164489 28721
BBSC JPMorgan BetaBuilders U.S. Small Cap Equity ETF 0.02 79.545
XRSU.L Xtrackers (IE) Public Limited Company - Xtrackers Russell 2000 UCITS ETF 0.0164489 391.785
ZPRR.DE SPDR Russell 2000 US Small Cap UCITS ETF 0.021888 64.96
R2SC.L SPDR Russell 2000 US Small Cap UCITS ETF 0.021888 56.58
BTEK.L iShares Nasdaq US Biotechnology UCITS ETF USD (Acc) 0.13 6.25
XRS2.DE Xtrackers Russell 2000 UCITS ETF 0.0164489 333.85
TRPL Pacer Metaurus US Large Cap Dividend Multiplier 300 ETF 0.04 41.14
JKJ iShares Morningstar Small-Cap ETF 0.01 231.193
VTS.AX Vanguard US Total Market Shares Index ETF 0.00158 481.52
CURE.AX Global X S&P Biotech ETF 0.2 60.17
VEMPX Vanguard Extended Market Index InstlPlus 0.00759 408.54
ITDG iShares Trust 0 39.567
ITDI iShares Trust 0 39.565
ITDH iShares Trust 0 39.575
ITDF iShares Trust 0 39.03
ITDC iShares Trust 0 35.21
ITDB iShares Trust 0 33.88
ITDD Integrated Data Corp. 0 36.69
ITDE iShares Trust 0 37.86
JDOC JPMorgan Healthcare Leaders ETF 0.17 58.8254
VSMPX Vanguard Total Stock Mkt Idx Instl Pls 0.00158 311.9
RSSL Global X Funds 0.02 103.93
SCDS JPMorgan Fundamental Data Science Small Core ETF 0.27 64.8619
RFLR Innovator ETFs Trust 0.04 29.76
ITDJ iShares Trust 0 30.745
RESM Columbia Research Enhanced Small Cap ETF 0.03 21.4991
TNXT T. Rowe Price Exchange-Traded Funds, Inc. - T. Rowe Price Innovation Leaders ETF 0.0851766 24.255
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