High dose and low dose of tsha-102 continue to be generally well tolerated with no treatment-related saes or dlts in all pediatric, adolescent and adult patients treated (high dose, n=6; low dose, n=4) across both reveal trials as of february 2025 data cutoff completed dosing of the 10 patients in part a of both reveal trials; maturing dataset continues to support advancement toward pivotal part b trial productive ongoing discussions with the fda to solidify regulatory pathway for tsha-102; update on pivotal trial design expected in h1 2025 clinical data from cohort two (high dose) and cohort one (low dose) of both reveal trials expected in h1 2025 conference call and live webcast today at 8:30 am eastern time dallas, feb. 26, 2025 (globe newswire) -- taysha gene therapies, inc. (nasdaq: tsha) (taysha or the company), a clinical-stage biotechnology company focused on advancing adeno-associated virus (aav)-based gene therapies for severe monogenic diseases of the central nervous system (cns), today reported financial results for the full year ended december 31, 2024, and provided a corporate update. “we are pleased with the pace at which our tsha-102 clinical program is advancing across a broad range of ages and stages of patients with rett syndrome.
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