Intra-cellular therapies presents data on antitumor effects of phosphodiesterase i inhibition in a preclinical colorectal cancer model at the 2021 american association for cancer research (aacr) annual meeting

Our research has demonstrated that the phosphodiesterase type 1 (pde1) enzyme modulates the immune system by reducing macrophage and microglial activity with demonstrated effects in neuroinflammatory conditions, cancer and cardiac diseases.
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