Publication of data from prospective, multicenter study demonstrates positive survival outcomes in patients with low-risk melanoma who avoided sentinel lymph node biopsy with information from castle biosciences' decisiondx®-melanoma test

Consistent with prior studies, published results from castle's decide study show decisiondx-melanoma can both accurately identify patients with less than 5% risk of sentinel lymph node (sln) positivity, who can safely consider forgoing the sentinel lymph node biopsy (slnb) surgical procedure, and who are also unlikely to experience disease progression 1,2 as of the last follow-up, all of the patients in the third study analysis with a low-risk decisiondx-melanoma test result (class 1a) were recurrence free, regardless of sln status 3 friendswood, texas, april 03, 2025 (globe newswire) -- castle biosciences, inc. (nasdaq: cstl), a company improving health through innovative tests that guide patient care, today announced the recent publication of two papers in the world journal of surgical oncology and cancer medicine sharing reports from the prospective, multicenter decide study demonstrating the significant impact of the company's decisiondx-melanoma test on slnb decision-making for patients with melanoma.3,4 slnb is a surgical procedure commonly used to determine whether a patient's melanoma has spread to nearby lymph nodes. while useful in the prognosis of patients for whom cancer is found in the lymph nodes, slnb returns a surgical result that is negative for metastasis in approximately 88% of patients who undergo the procedure.5 current national comprehensive cancer network® (nccn) guidelines suggest forgoing slnb when the likelihood of finding a positive sln is less than 5%, considering slnb when the risk is between 5-10% and offering the surgery when the likelihood of positivity is above 10%.
CSTL Ratings Summary
CSTL Quant Ranking