Alnylam to webcast conference call discussing third quarter 2014
financial results
Cambridge, mass.--(business wire)--alnylam pharmaceuticals, inc. (nasdaq: alny), a leading rnai therapeutics company, today announced that it will report financial results for the third quarter ending september 30, 2014 on wednesday, november 5, 2014, after the u.s. financial markets close. management will provide an update on the company, discuss third quarter 2014 results, and discuss expectations for the future via conference call on wednesday, november 5, 2014 at 4:30 p.m. et. to access the call, please dial 877-312-7507 (domestic) or 631-813-4828 (international) five minutes prior to the start time and refer to conference id 28235292. a replay of the call will be available beginning at 7:30 p.m. et on november 5, 2014. to access the replay, please dial 855-859-2056 (domestic) or 404-537-3406 (international), and refer to conference id 28235292. a live audio webcast of the call will also be available on the investors section of the company’s website, www.alnylam.com. an archived webcast will be available on the alnylam website approximately three hours after the event. about alnylam pharmaceuticalsalnylam is a biopharmaceutical company developing novel therapeutics based on rna interference, or rnai. the company is leading the translation of rnai as a new class of innovative medicines with a core focus on rnai therapeutics as genetic medicines, including programs as part of the company’s “alnylam 5x15™” product strategy. alnylam’s genetic medicine programs are rnai therapeutics directed toward genetically defined targets for the treatment of serious, life-threatening diseases with limited treatment options for patients and their caregivers. these include: patisiran (aln-ttr02), an intravenously delivered rnai therapeutic targeting transthyretin (ttr) for the treatment of ttr-mediated amyloidosis (attr) in patients with familial amyloidotic polyneuropathy (fap); aln-ttrsc, a subcutaneously delivered rnai therapeutic targeting ttr for the treatment of attr in patients with ttr cardiac amyloidosis, including familial amyloidotic cardiomyopathy (fac) and senile systemic amyloidosis (ssa); aln-at3, an rnai therapeutic targeting antithrombin (at) for the treatment of hemophilia and rare bleeding disorders (rbd); aln-cc5, an rnai therapeutic targeting complement component c5 for the treatment of complement-mediated diseases; aln-as1, an rnai therapeutic targeting aminolevulinic acid synthase-1 (alas-1) for the treatment of hepatic porphyrias including acute intermittent porphyria (aip); aln-pcs, an rnai therapeutic targeting pcsk9 for the treatment of hypercholesterolemia; aln-aat, an rnai therapeutic targeting alpha-1 antitrypsin (aat) for the treatment of aat deficiency-associated liver disease; aln-hbv, an rnai therapeutic targeting the hepatitis b virus (hbv) genome for the treatment of hbv infection; aln-tmp, an rnai therapeutic targeting tmprss6 for the treatment of beta-thalassemia and iron-overload disorders; aln-ang, an rnai therapeutic targeting angiopoietin-like 3 (angptl3) for the treatment of genetic forms of mixed hyperlipidemia and severe hypertriglyceridemia; aln-ac3, an rnai therapeutic targeting apolipoprotein c-iii (apociii) for the treatment of hypertriglyceridemia; aln-agt, an rnai therapeutic targeting angiotensinogen (agt) for the treatment of hypertensive disorders of pregnancy (hdp), including preeclampsia; aln-go1, an rnai therapeutic targeting glycolate oxidase (go) for the treatment of primary hyperoxaluria type 1 (ph1); and other programs yet to be disclosed. as part of its “alnylam 5x15” strategy, as updated in early 2014, the company expects to have six to seven genetic medicine product candidates in clinical development – including at least two programs in phase 3 and five to six programs with human proof of concept – by the end of 2015. the company’s demonstrated commitment to rnai therapeutics has enabled it to form major alliances with leading companies including merck, medtronic, novartis, biogen idec, roche, takeda, kyowa hakko kirin, cubist, glaxosmithkline, ascletis, monsanto, and the medicines company. in early 2014, alnylam and genzyme, a sanofi company, formed a multi-product geographic alliance on alnylam's genetic medicine programs in the rare disease field. specifically, alnylam will lead development and commercialization of programs in north america and europe, while genzyme will develop and commercialize products in the rest of world. in addition, alnylam and genzyme will co-develop and co-commercialize aln-ttrsc in north america and europe. in march 2014, alnylam acquired sirna therapeutics, a wholly owned subsidiary of merck. in addition, alnylam holds an equity position in regulus therapeutics inc., a company focused on discovery, development, and commercialization of microrna therapeutics. alnylam scientists and collaborators have published their research on rnai therapeutics in over 200 peer-reviewed papers, including many in the world’s top scientific journals such as nature, nature medicine, nature biotechnology, cell, new england journal of medicine, and the lancet. founded in 2002, alnylam maintains headquarters in cambridge, massachusetts. for more information, please visit www.alnylam.com.
