Actinium announces fda clearance of iomab-act targeted conditioning ind application for sickle cell disease patients undergoing bone marrow transplant in collaboration with columbia university
- sickle cell disease affects approximately 100,000 patients in the u.s. annually and is a debilitating and life-threatening condition with high unmet need - current conditioning with non-targeted chemotherapies provides limited access to potentially curative bone marrow transplant and recently approved gene therapies for sickle cell disease patients - initial trial focused on conditioning for bone marrow transplant intended to inform subsequent gene therapy conditioning study and provide broader access to cellular therapy for sickle cell patients new york , july 25, 2024 /prnewswire/ -- actinium pharmaceuticals, inc. (nyse american: atnm) (actinium or the company), a leader in the development of antibody radiation conjugates (arcs) and other targeted radiotherapies, today announced the fda clearance of an investigational new drug (ind) application to study iomab-act for targeted conditioning prior to a bone marrow transplant (bmt), in patients with sickle cell disease. the study will be conducted in collaboration with the columbia university and led by markus mapara, m.d.
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